A phase 2 trial of Biogen and Ionis Pharmaceuticals’ tau-targeting candidate missed its primary endpoint. But while the Alzheimer’s disease trial failed to yield the hoped-for dose-response data, ...

The Room Next Door star on overnight success, ‘sneaky follows’ from politicians and how internet commenting has dragged society down How did you get into comedy? I was submitting sketches to Spitting ...

All processes such as wound healing, hair growth, and the replacement of old cells with new ones depend on cell division. During this process, chromosomes inside the cell must be evenly divided ...

In Alzheimer’s disease, two key proteins, extracellular amyloid-beta plaques and an intercellular protein called tau, disrupt communication between the brain’s cells and lead to cell damage and death.

New research suggests Alzheimer’s arises not simply from plaques forming in the brain, but from one protein interfering with the normal job of another. For decades, much Alzheimer’s research has ...

In the era of A.I. agents, many Silicon Valley programmers are now barely programming. Instead, what they’re doing is deeply, deeply weird. Credit...Illustration by Pablo Delcan and Danielle Del Plato ...

Scientists have uncovered a surprising new role for little-known brain cells called tanycytes that may influence the development of Alzheimer’s disease. These specialized cells appear to help remove ...

In the quest to cure Alzheimer’s, the protein known as beta-amyloid has long taken center stage, driving development of a long list of drugs aimed at breaking up “amyloid plaques” in the brain. But ...

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia. Neurons with more of this garbage ...

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